منابع مشابه
Safety and complications of ocriplasmin: ocriplasmin, ocriplasmin; oh, how safe art thou?
Our ability to examine the vitreoretinal interface has been greatly improved by the invention of spectral-domain optical coherence tomography (OCT). It has allowedearlier andmore accurate diagnosis of abnormalities of vitreomacular adhesion (VMA) that may contribute to vision loss and may benefit fromintervention.While subtle abnormalitiesofVMAmay be observed, symptomatic VMA or that associated...
متن کاملOcriplasmin for Vitreoretinal Diseases
Fibronectin and laminin are clinically relevant plasmin receptors in the eye. Located at the vitreoretinal interface, they are cleaved by ocriplasmin (Microplasmin, ThromboGenics, Iselin, NJ), a novel ophthalmic medication. A series of clinical trials to study ocriplasmin for the treatment of vitreoretinal diseases such as vitreomacular traction, macular hole, and exudative age-related macular ...
متن کاملEffect of ocriplasmin on the management of macular holes: assessment of the clinical relevance of ocriplasmin.
IMPORTANCE Assessing the effect of ocriplasmin availability on the management of full-thickness macular holes (MHs) is important for vitreoretinal surgeons and their patients. Such an assessment can indicate whether the use of ocriplasmin will bring a paradigm shift in treating MHs or will be just an additional option relevant to a small group of patients. OBJECTIVES To classify the MHs evalu...
متن کاملMacular Hole Progression following Ocriplasmin Intravitreal Injection
Ocriplasmin is a protease which has been approved for the treatment of symptomatic vitreomacular adhesion (VMA). A 63-year-old presented with blurred vision in the left eye and a best corrected visual acuity of 6/18. Optical coherence tomography revealed VMA with an underlying macular hole and she subsequently underwent a left intravitreal ocriplasmin injection. One week after the injection, VM...
متن کاملRetinal breaks due to intravitreal ocriplasmin
Ocriplasmin represents a new treatment option for numerous vitreoretinopathies involving an abnormal vitreomacular interface. While the drug may circumvent the traditional risks of surgical treatment, pharmacologic vitreolysis is not devoid of risk itself. This report presents two cases, one of vitreomacular traction syndrome and the other of a full-thickness macular hole, both of which were tr...
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ژورنال
عنوان ژورنال: Graefe's Archive for Clinical and Experimental Ophthalmology
سال: 2016
ISSN: 0721-832X,1435-702X
DOI: 10.1007/s00417-016-3404-0